The Only Microbial Testing Method Validated on Cannabis. Period.

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The PathogINDICAtor® qPCR Microbial Detection Platform is the only method designed for and validated on cannabis flower, extracts, and a variety of infused products. PathogINDICAtor uses qPCR technology, an established safety testing method in the food industry and medicine that has been used in several peer-reviewed studies.

Fewer False Positives

PathogINDICAtor qPCR assays detect target organisms on a genetic level, searching for unique DNA sequences associated with each organism, or group of organisms. This prevents costly false positives. Conversely, research has shown culture-based methods often grow off-target organisms, leading to false positives and more pesticide usage.

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Fast Results

Next-day results mean your lab can handle more volume and your customers will spend less time waiting for their results. Also, Medicinal Genomics can assist with validation to make sure your lab is quickly up and running with microbial testing.

Scalable & Flexible

The qPCR-based platform was designed for a seamless transition to automation, and scripts for Hamilton robotics are available for immediate turnkey installation. The equipment can also be used to perform youPCR Point-of-Grow tests for plant gender, pests, and genetic markers.

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Fully Validated on Cannabis

Medicinal Genomics validated its PathogINDICAtor tests on a variety of cannabis matrices (flower, extract, and infused products) and provides extensive validation data upon request.

Internal Controls Included

Every PathogINDICAtor test reaction includes an internal cannabis control, which gives assurance that each reaction has proceeded correctly and results can be trusted. No other cannabis microbial testing platform includes internal cannabis controls.

Decontamination Protocol

PathogINDICAtor kits include an optional decontamination protocol that prevents genetic material from a previous test from contaminating subsequent test runs. The DREAM™ PCR decontamination protocol simplifies lab operations by eliminating the need for isolated pre- and post-PCR cleanup areas to prevent cross-test contamination. Read More

Hear from Labs Using PathogINDICAtor

  • We chose to use qPCR for microbial screening of cannabis at Digipath Labs for two reasons. First, Medicinal Genomics had already done the hard part, ie. creating the reagent kits for each microbial category and completing the validation on cannabis matrix to arrive at the more recognizable CFU/g conversion. That helps state regulators begin to understand the relationship of genomic screening to conventional plating methods such as 3M’s petrifilms. Second, there are many limitations with conventional plating methods (e.g. 3M’s petrifilms and BioMuirieux’s tube-based system). Medicinal Genomics' qPCR-based microbial detection platform allows for 48-hour turnaround of testing results and has built-in flexibility for the ever-changing state-by-state microbial testing guidelines. More importantly, qPCR provides an archived digital record of raw test results for those operating under ISO 17025 accreditation.

    Cindy Orser, Ph.D
    Cindy Orser, Ph.D Chief Science Officer, DigiPath Labs

Coverage for All State Requirements

Medicinal Genomics offers a variety of testing kits that cover each of the microbial tests that are required by the various state regulatory agencies. Medicinal Genomics also offers multiplex kits, which allow labs to test for multiple targets in one reaction, saving on time and labor, while increasing instrument run sample capacity by 33%.

New! Multiplex Kits:

E. coli and Salmonella
STEC E. coli and Salmonella
Total Enterobacteriaceae and Coliform

Individual Kits:

Total Yeast and Mold
Total Aerobic Count
Aspergillus niger
Aspergillus fumigatus
Aspergillus flavus
Aspergillus terreus

*All Medicinal Genomics chemicals and reagents are manufactured in a facility certified to ISO 9001 standards.

Research and Publications

Medicinal Genomics has done extensive research into the microbiome of the cannabis plant and shared its findings through peer-reviewed papers, articles, and videos. The hope is that these materials will educate the cannabis community about the many advantages of qPCR as a microbial testing method.

Cannabis microbiome sequencing reveals several mycotoxic fungi native to dispensary grade Cannabis flowers

The Live versus Dead Debate: Conflating Viability with Risk 

A discordant “Ring Test” in Cannabis microbiological safety testing resolved with Next Generation Sequencing