DNA Sequencing of the THC Synthase gene can provide valuable predictive medicinal information and better selective breeding information. THC Synthase is a highly polymorphic gene. Up to 16 SNPs in 200bp implies wide genetic diversity in this gene.
Both Industrial Hemp and Cannabis can be bred to be more productive and more medicinal. Genomic information can be a helpful tool here. Sequencing of THC, CBD, CBC, and other genes in the cannabinoid and terpene synthesis pathways are be shown to be predictive of Cannabinoid expression and in our understanding of the medicinal components of the plant.
Below is an annotation of Drug and Fiber Strain Genotypes of THC Synthase compared to CBD Synthase from Kojoma et al.
Medicinal Genomics Database of Cannabis Variants enables rapid and accurate genotyping and annotation of new strains.
Below one can see many SNPs in this novel strain aligning with genotypes and chemotypes of previously studied cultivar.
Amino Acid Alignments of multiple THC Synthase sequences.
Multiple Alignments of the Amino Acid sequence of the FAD binding domain of THC synthase. RSGGH at A.A. 112 to117.
